SPDR S&P Biotech ETF

$130.69

-4.16 (-3.08%)

Fund Overview by SPDR (State Street)

Equal-weighted biotech ETF. Gives small-cap clinical-stage biotech companies equal weight with large-cap pharma-like biotechs, creating a higher risk/reward profile. When biotech M&A heats up, XBI often outperforms.

AUM$6.5B

Expense Ratio0.35%

Holdings145

Dividend Yield0.1%

DistributionQuarterly

BenchmarkS&P Biotechnology Select Industry Index

InceptionJan 2006

ExchangeNYSEARCA

Price Data

Open$133.21

Prev Close$134.85

Day Range$130.30 — $133.67

52W Range$66.66 — $132.09

52-Week Range

$66.66 $132.09

From 52W High

-1.1%

From 52W Low

+96.1%

Investment Calculator

See how much dividend income XBI could generate based on its current price of $130.69 and 0.1% yield. Adjust the amount to estimate your quarterly distributions.

Investment amount

Shares Purchased76

Amount Invested$9,932.44

Annual Income$9.93

Monthly Income$0.83

Based on current dividend yield of 0.1%. Actual distributions may vary. Past dividends do not guarantee future payments.

Biotechnology ETF Comparison

ETF	Price	Change	Expense	AUM	Holdings	Yield
XBI SPDR S&P Biotech ETF	$130.69	-3.08%	0.35%	$6.5B	145	0.1%
IBB iShares Biotechnology ETF	$166.83	-2.63%	0.44%	$7.8B	224	0.2%
ARKG ARK Genomic Revolution ETF	$28.15	-3.53%	0.75%	$1.8B	35	0.0%

Top Biotechnology Stocks View all →

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ABBV Abbvie Inc	$214.50	+1.04%	372.39B
AMGN Amgen Inc	$338.63	+0.36%	179.23B
GILD Gilead Sciences Inc	$133.24	+2.10%	160.50B
VRTX Vertex Pharmaceuticals Inc	$435.46	+0.44%	114.32B
REGN Regeneron Pharmaceuticals	$634.20	-1.31%	73.89B
ALNY Alnylam Pharmaceuticals Inc	$296.86	-1.21%	38.43B
RVMD Revolution Medicines Inc	$153.73	+2.26%	30.97B
BIIB Biogen Inc	$189.47	+0.89%	28.63B
NTRA Natera Inc	$203.69	-0.60%	26.83B
UTHR United Therapeutics Corp	$568.75	+0.51%	24.36B

XBI FAQ

What is XBI?

XBI is the SPDR S&P Biotech ETF, an exchange-traded fund managed by SPDR (State Street). It tracks the S&P Biotechnology Select Industry Index and holds 145 Biotechnology securities with an expense ratio of 0.35%.

What is the expense ratio of XBI?

XBI charges an annual expense ratio of 0.35%, which means you pay $35.00 per year for every $10,000 invested. This fee is deducted automatically from the fund's returns.

Does XBI pay dividends?

Yes, XBI pays a 0.1% dividend yield, distributed quarterly. On a $10,000 investment, that works out to approximately $10.00 per year in dividend income.

What are the alternatives to XBI?

Other biotechnology ETFs include IBB, ARKG. Each offers different expense ratios, weighting methodologies, and number of holdings. Compare them in the ETF comparison table above to find the best fit for your portfolio.

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Last updated: May 16, 2026 at 9:45 PM ET